Article
HLA DRB allele polymorphisms and risk of cervical cancer associated with human papillomavirus infection: a population study in China.
European journal of gynaecological oncology - 1 Jan 2013
Zhao M, Qiu L, Tao N, Zhang L, Wu X, She Q, Zeng F, Wang Y, Wei S, Wu X
Abstract excerpt
OBJECTIVE: Persistent infection with high-risk human papillomavirus (HPV) is the main cause of cervical cancer. Environmental, behavioral, and ill-defined genetic factors have also been implicated in the pathogenesis of this disease. To determine whether human leukocyte antigen (HLA) DRB alleles are associated with cervical cancer and HPV infections in the Chinese population, HLA genotypes were examined in 69...
Topics
- Alleles
- China
- Female
- Genetic Predisposition to Disease
- HLA-DR beta-Chains
- Humans
- Logistic Models
- Papillomavirus Infections
- Polymorphism, Genetic
- Risk
- Uterine Cervical Neoplasms