Article
Diversity in the cag pathogenicity island of Helicobacter pylori isolates in populations from North and South India.
Journal of medical microbiology - 1 Jan 2010
Kumar Sushil, Kumar Ashok, Dixit Vinod Kumar
Abstract excerpt
The cag pathogenicity island (cagPAI) has been reported to be the major virulence determinant in Helicobacter pylori-related diseases. In the present study, the diversity of the cagA gene and the integrity of the cagPAI in 158 H. pylori strains from Varanasi (North India) and Hyderabad (South India) were studied by amplifying the cagA gene (approximately 3.5 kb), followed by PCR-RFLP analysis. The results...
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