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Article

Cybrid models of Parkinson's disease show variable mitochondrial biogenesis and genotype-respiration relationships.

Experimental neurology - 1 Dec 2009

Keeney Paula M, Dunham Lisa D, Quigley Caitlin K, Morton Stephanie L, Bergquist Kristen E, Bennett James P

Abstract excerpt

Sporadic Parkinson's disease (sPD) is a nervous system-wide disease that presents with a bradykinetic movement disorder and frequently progresses to include depression and cognitive impairment. Cybrid models of sPD are based on expression of sPD platelet mitochondrial DNA (mtDNA) in neural cells...

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Identifiers

PMID: 19815014
DOI: 10.1016/j.expneurol.2009.09.025
PMCID: PMC2783275

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19815014-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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