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The end of a myth: cloning and characterization of the ovine melatonin MT2 receptor

8 Oct 2009

Abstract excerpt

BACKGROUND AND PURPOSE: For many years, it was suspected that sheep expressed only one melatonin receptor (closely resembling MT(1) from other mammal species). Here we report the cloning of another melatonin receptor, MT(2), from sheep. EXPERIMENTAL APPROACH: Using a thermo-resistant reverse transcriptase and polymerase chain reaction primer set homologous to the bovine MT(2) mRNA sequence, we have cloned and...

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PMID: 19814723
DOI: 10.1111/j.1476-5381.2009.00453.x

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