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Article

Melatonin receptors in human fetal brain: 2‐[<sup>125</sup>I]iodomelatonin binding and MT1 gene expression

17 Oct 2002

Abstract excerpt

The purpose of this study was to identify sites of action of melatonin in the human fetal brain by in vitro autoradiography and in situ hybridization. Specific, guanosine triphosphate (GTP) sensitive, binding of 2-[(125)I]iodomelatonin was localized to the leptomeninges, cerebellum, thalamus, hypothalamus, and brainstem. In the hypothalalmus, specific binding was present in the suprachiasmatic nuclei (SCN) as...

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Identifiers

PMID: 12390504
DOI: 10.1034/j.1600-079x.2002.02921.x

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