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Article

Anthranilic sulfonamide CCK1/CCK2 dual receptor antagonists I: discovery of CCKR1 selectivity in a previously CCKR2-selective lead series.

Bioorganic & medicinal chemistry letters - 15 Nov 2009

Pippel Marna, Allison Brett D, Phuong Victor K, Li Lina, Morton Magda F, Prendergast Clodagh, Wu Xiaodong, Shankley Nigel P, Rabinowitz Michael H

Abstract excerpt

A series of CCK2R-selective anthranilic amides is shown to derive CCK1R affinity via selective substitution of the amide side chain. Thus, extending the length of the original benzamide side chain by a single methylene unit imparts CCK1R affinity to the series, and further fine tuning of the affi...

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Source

Identifiers

PMID: 19811913
DOI: 10.1016/j.bmcl.2009.09.064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19811913-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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