Article
Susceptibility locus on chromosome 1q23-25 for a schizophrenia subtype resembling deficit schizophrenia identified by latent class analysis.
Archives of general psychiatry - 1 Oct 2009
Holliday Elizabeth G, McLean Duncan E, Nyholt Dale R, Mowry Bryan J
Abstract excerpt
CONTEXT: Identifying susceptibility genes for schizophrenia may be complicated by phenotypic heterogeneity, with some evidence suggesting that phenotypic heterogeneity reflects genetic heterogeneity. OBJECTIVE: To evaluate the heritability and conduct genetic linkage analyses of empirically derived, clinically homogeneous schizophrenia subtypes. DESIGN: Latent class and linkage analysis. SETTING: Taiwanese field...
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