Article
Sequencing and comparative analysis of fugu protocadherin clusters reveal diversity of protocadherin genes among teleosts.
BMC evolutionary biology - 30 Mar 2007
Yu Wei-Ping, Yew Kenneth, Rajasegaran Vikneswari, Venkatesh Byrappa
Abstract excerpt
BACKGROUND: The synaptic cell adhesion molecules, protocadherins, are a vertebrate innovation that accompanied the emergence of the neural tube and the elaborate central nervous system. In mammals, the protocadherins are encoded by three closely-linked clusters (alpha, beta and gamma) of tandem genes and are hypothesized to provide a molecular code for specifying the remarkably-diverse neural connections in the...
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