Circling behavior exhibited by a transgenic insertional mutant.

doi:10.1016/0169-328x(90)90050-n

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Article

Circling behavior exhibited by a transgenic insertional mutant.

Brain research. Molecular brain research - 1 Oct 1990

Ratty A K, Fitzgerald L W, Titeler M, Glick S D, Mullins J J, Gross K W

Abstract excerpt

We report here of an abnormal circling behavior expressed in the TgX15 transgenic mouse line as a result of insertional mutagenesis. Homozygous transgenic mice expressed the phenotype while heterozygous transgenics were normal. We also found that the dopamine D2 receptor binding sites in the stri...

Topics

Animals
Behavior, Animal
Mice
Mice, Transgenic
Mutagenesis, Insertional
Neurotransmitter Agents
Phenotype
Receptors, Dopamine
Receptors, Dopamine D2
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