Article
Identifying individuals in a complex mixture of DNA with unknown ancestry.
Statistical applications in genetics and molecular biology - 1 Jan 2009
Sampson Joshua, Zhao Hongyu
Abstract excerpt
A new test was recently developed that could use a high-density set of single nucleotide polymorphisms (SNPs) to determine whether a specific individual contributed to a mixture of DNA. The test statistic compared the genotype for the individual to the allele frequencies in the mixture and to the allele frequencies in a reference group. This test requires the ancestries of the reference group to be nearly...
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