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[Detection of JAK2V617F mutation and its clinical significance in 80 patients with M2 acute myelogenous leukemia].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 May 2009

Shen Yi-min, Chao Hong-ying, Zhang Ri, Li Wei-yang, Feng Yu-feng, Zhu Zi-ling, Xue Yong-quan

Abstract excerpt

OBJECTIVE: To explore the prevalence and prognostic significance of JAK2V617F gene mutation in acute myelogenous leukemia M2 (AML-M2) patients. METHODS: Allele specific polymerase chain reaction (PCR) was used to detect JAK2 gene mutation. RESULTS: Of 80 de novo AML-M2 patients, 6 at the time of first diagnosis and 1 at relapse were found to have JAK2V617F gene mutation (8.8%, 7/80). Morphologically, the whole...

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Identifiers

PMID: 19799086

Genes

JAK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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