Article
[Biological characteristics of bone marrow mesenchymal stem cells and JAK2 mutation in myeloproliferative neoplasms].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Sept 2012
Tian Hong, Chen Guang-Hua, Xu Yang, Wang Rong-Xian, Qiao Man, Liu Hui-Wen, Wu De-Pei
Abstract excerpt
OBJECTIVE: To study the biological characteristics of bone marrow mesenchymal stem cells (BMSCs) and detect JAK2 mutation in BMSCs from myeloproliferative neoplasms (MPN) patients. METHODS: JAK2 V617F mutation and exon 12 mutation in 70 MPN patients' blood or bone marrow samples were detected. Isolated BMSCs were then characterized their phenotype, mesenchymal differentiation capacity and existence of JAK2...
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