Article
Environmental and genetic factors influence the relationship between circulating IL-10 and obesity phenotypes.
Obesity (Silver Spring, Md.) - 1 Mar 2010
Bassols Judit, Botas Patricia, Moreno-Navarrete Jose M, Delgado Elias, Ortega Francisco, Ricart Wifredo, Fernandez-Real Jose M
Abstract excerpt
Interleukin-10 (IL-10) is a centrally operating anti-inflammatory cytokine that plays a crucial role in the regulation of the innate immune system. It has strong inactivating properties on the inflammatory host response and has been related with viral persistence. We aimed to evaluate the association among circulating IL-10, obesity phenotypes, IL-10 and IL-10R1 gene polymorphisms, and the environmental exposure...
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