Article
Purinergic receptor P2Y, G-protein coupled, 12 gene variants and risk of incident ischemic stroke, myocardial infarction, and venous thromboembolism.
Atherosclerosis - 1 Apr 2008
Zee Robert Y L, Michaud Sherri E, Diehl Kirsti A, Chasman Daniel I, Emmerich Joseph, Gaussem Pascale, Aiach Martine, Ridker Paul M
Abstract excerpt
Recent data have implicated a haplotype of the purinergic receptor P2Y, G-protein coupled, 12 gene (P2RY12), as potential risk determinant for atherothrombosis. However, to date, no prospective, genetic-epidemiological data are available. Using DNA samples collected at baseline in a prospective cohort of 14,916 initially healthy American men, we examined the possible association of P2RY12 genetic variants, in...
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