A comparison of neurological, metabolic, structural, and genetic evaluations in persons at risk for Huntington's disease.

doi:10.1002/ana.410280503

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Article

A comparison of neurological, metabolic, structural, and genetic evaluations in persons at risk for Huntington's disease.

Annals of neurology - 1 Nov 1990

Grafton S T, Mazziotta J C, Pahl J J, St George-Hyslop P, Haines J L, Gusella J, Hoffman J M, Baxter L R, Phelps M E

Abstract excerpt

We compared four diagnostic data sets for the assessment of individuals at risk for Huntington's disease. Fifty-four chorea-free persons were evaluated by neurological examination, positron emission tomography measurement of glucose metabolism, radiographic computerized tomographic measurement of...

Topics

Atrophy
Caudate Nucleus
Frontal Lobe
Globus Pallidus
Glucose
Heterozygote
Humans
Huntington Disease
Neurologic Examination
Phenotype
Polymorphism, Restriction Fragment Length
Predictive Value of Tests
Putamen
Tomography, Emission-Computed
Tomography, X-Ray Computed

Source

Open in PubMed

Identifiers

PMID: 1979723
DOI: 10.1002/ana.410280503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1979723-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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