Article
Resolution of remodeling in eosinophilic esophagitis correlates with epithelial response to topical corticosteroids.
Allergy - 1 Jan 2010
Aceves S S, Newbury R O, Chen D, Mueller J, Dohil R, Hoffman H, Bastian J F, Broide D H
Abstract excerpt
BACKGROUND: Esophageal remodeling occurs in eosinophilic esophagitis (EE) patients but whether the components of remodeling in the subepithelium are reversible by administration of topical oral corticosteroids is unknown. METHODS: We quantitated the degree of lamina propria remodeling in esophageal biopsies obtained before and after at least 3 months of therapy with budesonide in 16 pediatric EE subjects. In...
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