Article
Concurrent Lpin1 and Nrcam mouse mutations result in severe peripheral neuropathy with transitory hindlimb paralysis.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 30 Sept 2009
Douglas Darlene S, Moran Jennifer L, Bermingham John R, Chen Xiang-Jun, Brindley David N, Soliven Betty, Beier David R, Popko Brian
Abstract excerpt
Peripheral neuropathy is a broad category of disorders with a diverse etiology, grouped together by their common pathogenic effect on the peripheral nervous system (PNS). Because of the heterogeneity observed to be responsible for these disorders, a forward genetics method of gene discovery was used to identify additional affected pathways. In this report, we describe the mutant mouse line 20884, generated by...
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