Article
Replication stress leads to genome instabilities in Arabidopsis DNA polymerase delta mutants.
The Plant cell - 1 Sept 2009
Schuermann David, Fritsch Olivier, Lucht Jan M, Hohn Barbara
Abstract excerpt
Impeded DNA replication or a deficiency of its control may critically threaten the genetic information of cells, possibly resulting in genome alterations, such as gross chromosomal translocations, microsatellite instabilities, or increased rates of homologous recombination (HR). We examined an Arabidopsis thaliana line derived from a forward genetic screen, which exhibits an elevated frequency of somatic HR....
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