Article
Comparison of RFLP-DR beta and serological HLA-DR typing in 1500 individuals.
Transplantation - 1 Nov 1990
Mytilineos J, Scherer S, Opelz G
Abstract excerpt
A group of 1522 individuals were HLA-DR-typed both by the standard serological technique and by the RFLP method. Whereas 11% (n = 164) of the serological typings were technically unsuccessful or doubtful, all typings were successful by RFLP. The results of the remaining 1358 typings revealed a serological error rate of 25%. In 16% a serological "blank" turned out to be a definable allele by RFLP, while in 9% an...
Topics
- Alleles
- HLA-DR Antigens
- Histocompatibility Testing
- Humans
- Polymorphism, Restriction Fragment Length
- Serotyping
- Transplantation Immunology
