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Article

Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis.

Annals of the rheumatic diseases - 1 Mar 2010

Gourh Pravitt, Arnett Frank C, Tan Filemon K, Assassi Shervin, Divecha Dipal, Paz Gene, McNearney Terry, Draeger Hilda, Reveille John D, Mayes Maureen D, Agarwal Sandeep K

Abstract excerpt

OBJECTIVE: It is increasingly being appreciated that multiple autoimmune diseases share common susceptibility genes. The tumour necrosis factor ligand superfamily member 4 gene (TNFSF4, OX40L), which encodes for the T cell costimulatory molecule OX40 ligand, has been identified as a susceptibility gene for the development of systemic lupus erythematosus (SLE). Accordingly, the aim of the current study was to...

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Source

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Identifiers

PMID: 19778912
DOI: 10.1136/ard.2009.116434
PMCID: PMC2927683

Genes

TNFSF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis.PMID 19778912Read ↗

A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort.Semantic proximity Read ↗

Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus.Semantic proximity Read ↗

The molecular genetic basis of the association of TNFSF4 with SLESemantic proximity Read ↗

TNFSF4 polymorphisms are associated with systemic lupus erythematosus in the Malaysian population.Semantic proximity Read ↗

Association of TNFSF4 polymorphisms with systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

Replication of the TNFSF4 (OX40L) promoter region association with systemic lupus erythematosus.Semantic proximity Read ↗

Independent replication and meta analysis of association studies establish TNFSF4 as a susceptibility gene preferentially associated with the subset of anticentromere-positive patients with systemic sclerosis.Semantic proximity Read ↗

Associations between TNFSF4 gene polymorphisms (rs2205960 G > A, rs704840 T > G and rs844648 G > A) and susceptibility to autoimmune diseases in Asians: a meta-analysis.Semantic proximity Read ↗

Association of TNFSF4 Gene Polymorphisms and Plasma TNFSF4 Level with Risk of Systemic Lupus Erythematosus in a Chinese Population.Semantic proximity Read ↗

Association of TNFSF4 polymorphisms with systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

Associations between TNFSF4 and TRAF1-C5 gene polymorphisms and systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

Association of the TNFAIP3 rs5029939 variant with systemic sclerosis in the European Caucasian population.Semantic proximity Read ↗

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