Article
Open-sandwich enzyme immunoassay for one-step noncompetitive detection of corticosteroid 11-deoxycortisol.
Analytical chemistry - 15 Oct 2009
Ihara Masaki, Suzuki Tatsuya, Kobayashi Norihiro, Goto Junichi, Ueda Hiroshi
Abstract excerpt
A noncompetitive immunoassay has the potential for improved sensitivity and working range compared with corresponding competitive assays. However, monovalent antigens with less than 1000 in molecular weight are not susceptible to sandwich assays due to their small size. As a noncompetitive immunoassay that can be performed with a clone of an antibody, an open-sandwich immunoassay (OS-IA) based on the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.