Article
Mechanical stretch regulates hypertrophic phenotype of the myometrium during pregnancy.
Reproduction (Cambridge, England) - 1 Jan 2010
Shynlova Oksana, Kwong Ruth, Lye Stephen J
Abstract excerpt
The adaptive growth of the uterus is a critical event that involves changes in cellular phenotypes throughout pregnancy. In early pregnancy, uterine growth is due to hyperplasia of uterine smooth muscle cells (SMCs) within the myometrium; however, the major component of myometrial growth occurs after mid-gestation. This study sought to test the hypothesis that increase in myometrial growth seen during late...
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