The utility of a HindIII polymorphism of factor VIII examined by rapid DNA analysis.

doi:10.1111/j.1365-2141.1990.tb07839.x

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Article

The utility of a HindIII polymorphism of factor VIII examined by rapid DNA analysis.

British journal of haematology - 1 Sept 1990

Graham J B, Kunkel G R, Fowlkes D M, Lord S T

Abstract excerpt

A previously described HindIII restriction fragment length polymorphism (RFLP) of factor VIII (FVIII) has its polymorphic site in the unsequenced nineteenth intron. We have located the polymorphic site, as well as an invariant site, by amplifying and sequencing IVS 19 using the polymerase chain r...

Topics

Alleles
Base Sequence
Blotting, Southern
Factor VIII
Female
Humans
Linkage Disequilibrium
Male
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Racial Groups

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