Article
Class prediction models of thrombocytosis using genetic biomarkers.
Blood - 7 Jan 2010
Gnatenko Dmitri V, Zhu Wei, Xu Xiao, Samuel Edward T, Monaghan Melissa, Zarrabi Mohammad H, Kim Christi, Dhundale Anil, Bahou Wadie F
Abstract excerpt
Criteria for distinguishing among etiologies of thrombocytosis are limited in their capacity to delineate clonal (essential thrombocythemia [ET]) from nonclonal (reactive thrombocytosis [RT]) etiologies. We studied platelet transcript profiles of 126 subjects (48 controls, 38 RT, 40 ET [24 contained the JAK2V(617)F mutation]) to identify transcript subsets that segregated phenotypes. Cross-platform consistency...
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