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Article

DeltaNp63 overexpression, alone and in combination with other biomarkers, predicts the development of oral cancer in patients with leukoplakia.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2009

Saintigny Pierre, El-Naggar Adel K, Papadimitrakopoulou Vali, Ren Hening, Fan You-Hong, Feng Lei, Lee J Jack, Kim Edward S, Hong Waun Ki, Lippman Scott M, Mao Li

Abstract excerpt

PURPOSE: The risk of malignant transformation of oral preneoplastic lesion (OPL) is difficult to assess. DeltaNp63 is an early oncoprotein associated with mucosal tumorigenesis. The purpose of this study was to assess DeltaNp63 expression in OPL and its role as a marker of oral cancer risk. EXPERIMENTAL DESIGN: DeltaNp63 expression was determined using immunohistochemistry in 152 OPL patients included in a...

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Identifiers

PMID: 19773378
DOI: 10.1158/1078-0432.CCR-09-0498
PMCID: PMC2756317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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