Article
Gene expression profiling: classification of mice with left ventricle systolic dysfunction using microarray analysis.
Critical care medicine - 1 Jan 2010
Wong Jim, Chang Christine, Agrawal Rani, Walton G Brant, Chen Craig, Murthy Ashwin, Patterson Andrew J
Abstract excerpt
OBJECTIVE: We tested the hypothesis that a set of differentially expressed genes could be used to classify mice according to cardiovascular phenotype after prolonged catecholamine stress. DESIGN: Prospective, randomized study. SETTING: University-based research laboratory. SUBJECTS: One hundred seventy-three male mice were studied: wild-type (WT) C57, WT FVB, WT B6129SF2/J, and beta2 adrenergic receptor knockout....
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