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Article

Breast cancer gene variants: separating the harmful from the harmless.

The Journal of clinical investigation - 1 Oct 2009

Domchek Susan M, Greenberg Roger A

Abstract excerpt

Individuals carrying a mutation in the breast cancer 1, early onset gene (BRCA1) are at increased risk of breast or ovarian cancer and thus are candidates for risk reduction strategies such as oophorectomy and mastectomy. A recurring problem in the clinic is that many detectable changes within th...

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Source

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Identifiers

PMID: 19770511
DOI: 10.1172/JCI40577
PMCID: PMC2752087

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19770511-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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