Article
High-throughput SNP genotyping: combining tag SNPs and molecular beacons.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Barreiro Luis B, Henriques Ricardo, Mhlanga Musa M
Abstract excerpt
In the last decade, molecular beacons have emerged to become a widely used tool in the multiplex typing of single nucleotide polymorphisms (SNPs). Improvements in detection technologies in instrumentation and chemistries to label these probes have made it possible to use up to six spectrally dist...
Topics
- Cell Adhesion Molecules
- DNA Primers
- Fluorescent Dyes
- Genetic Loci
- Genotype
- High-Throughput Screening Assays
- Humans
- Lectins, C-Type
- Molecular Probes
- Polymorphism, Single Nucleotide
- Receptors, Cell Surface
- Reverse Transcriptase Polymerase Chain Reaction