Article
High-throughput SNP genotyping: combining tag SNPs and molecular beacons.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Barreiro Luis B, Henriques Ricardo, Mhlanga Musa M
Abstract excerpt
In the last decade, molecular beacons have emerged to become a widely used tool in the multiplex typing of single nucleotide polymorphisms (SNPs). Improvements in detection technologies in instrumentation and chemistries to label these probes have made it possible to use up to six spectrally distinguishable probes per reaction well. With the remarkable advances made in the characterization of human genome...
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