SNP discovery and typing technologies for pharmacogenomics.

doi:10.2174/1568026043387656

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Article

SNP discovery and typing technologies for pharmacogenomics.

Current topics in medicinal chemistry - 1 Jan 2004

Twyman Richard M

Abstract excerpt

Genetic variation in the human genome occurs predominantly as single nucleotide polymorphisms (SNPs). Our DNA may contain as many as ten million SNPs, of which three million or more are likely to differ between any two unrelated individuals. These three million genetic differences make a significant contribution to the observed variation in complex human phenotypes, such as disease susceptibility and our...

Topics

Genetic Testing
Genome, Human
Genotype
Humans
Pharmacogenetics
Polymorphism, Single Nucleotide
Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 15379655
DOI: 10.2174/1568026043387656

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