Article
The impact of population size on the evolution of asexual microbes on smooth versus rugged fitness landscapes.
BMC evolutionary biology - 18 Sept 2009
Handel Andreas, Rozen Daniel E
Abstract excerpt
BACKGROUND: It is commonly thought that large asexual populations evolve more rapidly than smaller ones, due to their increased rate of beneficial mutations. Less clear is how population size influences the level of fitness an asexual population can attain. Here, we simulate the evolution of bacteria in repeated serial passage experiments to explore how features such as fitness landscape ruggedness, the size of...
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