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Article

Polymorphisms in MMP9 and SIPA1 are associated with increased risk of nodal metastases in early-stage cervical cancer.

Gynecologic oncology - 1 Mar 2010

Brooks Rebecca, Kizer Nora, Nguyen Loan, Jaishuen Atthapon, Wanat Karolyn, Nugent Elizabeth, Grigsby Perry, Allsworth Jenifer E, Rader Janet S

Abstract excerpt

OBJECTIVE: Heritable polymorphisms modulate metastatic efficiency in Cancer Single nucleotide polymorphisms (SNPs) in MMP9 (rs17576) and SIPA1 (rs746429, rs931127) have been associated with nodal metastases in multiple cancers. We investigated the association of these SNPs with nodal metastases in early-stage cervical cancer. METHODS: Consecutive patients with stage IB cervical cancer who underwent a pelvic lymph...

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Source

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Identifiers

PMID: 19906411
DOI: 10.1016/j.ygyno.2009.09.037
PMCID: PMC2822070

Genes

SIPA1
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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