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Article

Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism.

Journal of neurochemistry - 1 Nov 2009

Gal Jozsef, Ström Anna-Lena, Kwinter David M, Kilty Renée, Zhang Jiayu, Shi Ping, Fu Weisi, Wooten Marie W, Zhu Haining

Abstract excerpt

The p62/sequestosome 1 protein has been identified as a component of pathological protein inclusions in neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). P62 has also been implicated in autophagy, a process of mass degradation of intracellular proteins and organelles. Auto...

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Source

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Identifiers

PMID: 19765191
DOI: 10.1111/j.1471-4159.2009.06388.x
PMCID: PMC2766427

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19765191-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism.PMID 19765191Read ↗

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