Article
Association of PLA2G7 polymorphisms with carotid atherosclerosis in hypertensive Japanese.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Dec 2009
Miwa Yoshikazu, Kamide Kei, Takiuchi Shin, Yoshii Masayoshi, Horio Takeshi, Tanaka Chihiro, Banno Mariko, Miyata Toshiyuki, Kawano Yuhei
Abstract excerpt
Although the plasma platelet-activating factor-acetylhydrolase (pPAF-AH) gene (PLA2G7) polymorphisms are reportedly associated with atherosclerotic diseases, their effects in hypertensive patients have not been well examined. Thus, we genotyped V279F, a loss-of-function mutation commonly seen in the Japanese, and I198T and A379V commonly seen in Caucasians, and investigated the (1) ethnic differences in the...
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