Article
Flexible automated platform for blood group genotyping on DNA microarrays.
The Journal of molecular diagnostics : JMD - 1 May 2014
Paris Sandra, Rigal Dominique, Barlet Valérie, Verdier Martine, Coudurier Nicole, Bailly Pascal, Brès Jean-Charles
Abstract excerpt
The poor suitability of standard hemagglutination-based assay techniques for large-scale automated screening of red blood cell antigens severely limits the ability of blood banks to supply extensively phenotype-matched blood. With better understanding of the molecular basis of blood antigens, it is now possible to predict blood group phenotype by identifying single-nucleotide polymorphisms in genomic DNA....
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