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False-Negative Results of a Validated Real-Time PCR Protocol for Diagnosis of Newcastle Disease Due to Genetic Variability of the Matrix Gene

17 Sept 2009

Abstract excerpt

Newcastle disease (ND) is an OIE (World Organization for Animal Health) notifiable disease affecting many species of birds and causing severe economic losses in the poultry sector. The disease is caused by virulent avian paramyxoviruses of serotype 1 (APMV-1). As for many other RNA viruses, the genetic variability of APMV-1 is significant. Genetic analysis has revealed the existence of two main clades, namely...

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PMID: 19759219
DOI: 10.1128/jcm.00895-09

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