Article
Application of highly polymorphic DNA markers to the identification of HeLa cell sublines.
In vitro cellular & developmental biology : journal of the Tissue Culture Association - 1 Jan 2000
Kataoka E, Honma M, Ohnishi K, Sofuni T, Mizusawa H
Abstract excerpt
Polymorphic DNA markers were used to identify eight sublines derived from HeLa. Using five highly polymorphic minisatellite DNA probes, these cell lines were distinguished and classified into six groups by Southern blot analysis. Polymorphic DNA markers, therefore, can provide a useful tool for monitoring genetic changes of a cell line during culture and for distinguishing sublines derived from the same origin.
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