Article
Online verification of human cell line identity by STR DNA typing.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Dirks Wilhelm G, Drexler Hans G
Abstract excerpt
The main prerequisition for any research, development, or production programs involving cell lines is whether a cell line is authentic or not. Microsatellites in the human genome harboring short tandem repeat (STR) DNA markers allow the identification of individual cell lines at the DNA level. Polymerase chain reaction (PCR) amplification of eight highly polymorphic microsatellite STR loci and gender...
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