Article
[Association between polymorphism in uncoupling proteins and type 2 diabetes in a northwestern Colombian population].
Biomedica : revista del Instituto Nacional de Salud - 1 Mar 2009
Franco-Hincapié Liliana, Duque Constanza Elena, Parra María Victoria, Gallego Natalia, Villegas Alberto, Ruiz-Linares Andrés, Bedoya Gabriel
Abstract excerpt
INTRODUCTION: The uncoupling proteins belong to the family of anion transporting proteins which uncouple the ATP production from the mitochondrial respiration, cause proton leakage through the inner mitochondrial membrane, and release energy as heat. Although uncoupling protein function has not been well established, specific polymorphisms in these proteins have been associated with type 2 diabetes mellitus,...
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