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Article

Muscarinic acetylcholine receptor 1 gene polymorphisms associated with high myopia.

Molecular vision - 4 Sept 2009

Lin Hui-Ju, Wan Lei, Tsai Yuhsin, Chen Wen-Chi, Tsai Shih-Wei, Tsai Fuu-Jen

Abstract excerpt

PURPOSE: Numerous studies, including those using animal models of myopia development and human clinical trials, have shown that the non-selective muscarinic antagonist atropine is effective in preventing the axial elongation that leads to myopia development. Among all of the muscarinic acetylcholine receptors (mAChRs), mAChR 1 (M1) was the most effective in preventing myopic eye change. Our specific aim in this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19753311
PMCID: PMC2742638

Genes

CHRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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