Article
Deletions of chromosomal regions coding for fimbriae and hemolysins occur in vitro and in vivo in various extraintestinal Escherichia coli isolates.
Microbial pathogenesis - 1 Mar 1990
Hacker J, Bender L, Ott M, Wingender J, Lund B, Marre R, Goebel W
Abstract excerpt
Fimbrial adhesins and hemolysins contribute to pathogenicity of extraintestinal Escherichia coli isolates causing urinary tract infections (UTI), sepsis and new born meningitis (NBM). Using gene cloning techniques and pulse field electrophoresis in combination with Southern hybridizations it was demonstrated that the genetic determinants coding for P and 'P-related' fimbrial adhesins and hemolysins are closely...
Topics
- Adhesins, Escherichia coli
- Animals
- Bacterial Adhesion
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Bacterial Toxins
- Chromosome Deletion
- DNA, Bacterial
- Escherichia coli
- Escherichia coli Proteins