Article
Activation of CD4+ lymphocytes by syngeneic brain microvascular smooth muscle cells.
Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 1990
Fabry Z, Waldschmidt M M, Van Dyk L, Moore S A, Hart M N
Abstract excerpt
Splenocyte proliferation as measured by [3H]thymidine incorporation was detected when brain microvessel smooth muscle cells (SM) were cocultured with syngeneic spleen cells. This report focuses on the role of different lymphocyte populations in this activation. The central role of CD4+ T cells in...
Topics
- Animals
- Antibodies, Monoclonal
- Brain
- CD4 Antigens
- CD4-Positive T-Lymphocytes
- Female
- Histocompatibility Antigens Class II
- Lymphocyte Activation
- Mice
- Mice, Inbred BALB C
- Muscle, Smooth, Vascular
- Phenotype
- Spleen
- T-Lymphocytes, Regulatory
- Vasculitis