Article
Cyclooxygenase-2 polymorphisms confer susceptibility to sarcoidosis but are not related to prognosis.
Respiratory medicine - 1 Mar 2009
Lopez-Campos José Luis, Rodriguez-Rodriguez David, Rodriguez-Becerra Eulogio, Alfageme Michavila Inmaculada, Guerra Jose Fernandez, Hernandez Francisco Javier García, Casanova Alvaro, Fernández de Córdoba Gamero Javier, Romero-Ortiz Ana, Arellano-Orden Elena, Montes-Worboys Ana
Abstract excerpt
BACKGROUND: The aim of this multicenter study was to investigate the relationship between single nucleotide polymorphisms (SNPs) of the cyclooxygenase-2 (COX2) gene and susceptibility to sarcoidosis, as well as the relation between these SNPs and the evolution of the disease. MATERIAL AND METHODS: This multicenter investigation involved seven hospitals in Spain. We used a case-control design followed by a...
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