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Article

Identification of the Transcription Factor Single-Minded Homologue 2 as a Potential Biomarker and Immunotherapy Target in Prostate Cancer

8 Sept 2009

Abstract excerpt

PURPOSE: Identification of novel biomarkers and immunotherapy targets for prostate cancer (PCa) is crucial to better diagnosis and therapy. We sought to identify novel PCa tumor-associated antigens (TAA) that are expressed in PCa, absent in nonprostate human tissue, and immunogenic for immune responses restricted by human HLA. EXPERIMENTAL DESIGN AND RESULTS: Using microarray analysis of normal and cancerous...

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PMID: 19737960
DOI: 10.1158/1078-0432.ccr-09-0911

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