Article
Dihydropyridines decrease X-ray-induced DNA base damage in mammalian cells.
Mutation research - 1 Dec 2009
Wojewódzka M, Gradzka I, Buraczewska I, Brzóska K, Sochanowicz B, Goncharova R, Kuzhir T, Szumiel I
Abstract excerpt
Compounds with the structural motif of 1,4-dihydropyridine display a broad spectrum of biological activities, often defined as bioprotective. Among them are L-type calcium channel blockers, however, also derivatives which do not block calcium channels exert various effects at the cellular and organismal levels. We examined the effect of sodium 3,5-bis-ethoxycarbonyl-2,6-dimethyl-1,4-dihydropyridine-4-carboxylate...
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