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Article

EFHC1 interacts with microtubules to regulate cell division and cortical development.

Nature neuroscience - 1 Oct 2009

de Nijs Laurence, Léon Christine, Nguyen Laurent, Loturco Joseph J, Delgado-Escueta Antonio V, Grisar Thierry, Lakaye Bernard

Abstract excerpt

Mutations in the EFHC1 gene are linked to juvenile myoclonic epilepsy (JME), one of the most frequent forms of idiopathic generalized epilepsies. JME is associated with subtle alterations of cortical and subcortical architecture, but the underlying pathological mechanism remains unknown. We found...

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Source

Identifiers

PMID: 19734894
DOI: 10.1038/nn.2390

Genes

EFHC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19734894-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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EFHC1 interacts with microtubules to regulate cell division and cortical development.PMID 19734894Read ↗

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