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Article

Prion dementia without characteristic pathology.

Lancet (London, England) - 7 Jul 1990

Collinge J, Owen F, Poulter M, Leach M, Crow T J, Rossor M N, Hardy J, Mullan M J, Janota I, Lantos P L

Abstract excerpt

Gerstmann-Sträussler syndrome (GSS) was diagnosed in a family with presenile dementia by prion protein gene analysis. Extensive histological examination of the brain of an affected individual from this family showed no characteristic features of GSS or Creutzfeldt-Jakob disease (CJD). Thus "spongiform encephalopathy" (GSS or CJD) cannot always be excluded on neuropathological grounds in an individual dying of a...

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Identifiers

PMID: 1973256
DOI: 10.1016/0140-6736(90)91518-f

Genes

GSS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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