Article
Identification of hemochromatosis gene polymorphisms in chronically transfused patients with sickle cell disease.
American journal of hematology - 1 Dec 2003
Jeng Michael R, Adams-Graves Patricia, Howard Thad A, Whorton Matthew R, Li Chin-Shang, Ware Russell E
Abstract excerpt
Three polymorphic gene mutations in the human hemochromatosis (HFE) gene (C282Y, H63D, S65C) are associated with non-transfusion-related iron overload in Caucasians. More recently, these mutations have also been identified in African-Americans. However, the prevalence of HFE gene mutations in African-Americans with sickle cell disease (SCD) has not been described. The presence of these mutations in this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.