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Article

A role for the MAPK/ERK pathway in oligodendroglial differentiation in vitro: stage specific effects on cell branching.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Dec 2009

Younes-Rapozo V, Felgueiras L O R, Viana N L, Fierro I M, Barja-Fidalgo C, Manhães A C, Barradas P C

Abstract excerpt

The mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) pathway is important for both long-term survival and timing of the progression of oligodendrocyte differentiation. Oligodendroglial cells treated with MEK inhibitor were distinguished by using stage specific markers: NG2 proteoglycan, A2B5, 2'3'nucleotide-cyclic 3'phosphodiesterase (CNPase) and myelin basic protein (MBP), and...

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Identifiers

PMID: 19729058
DOI: 10.1016/j.ijdevneu.2009.08.014

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MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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