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Article

Functional genome screen for therapeutic targets of osteosarcoma

10 Aug 2009

Abstract excerpt

Osteosarcoma (OS) is the most frequent primary malignant bone tumor of children and young adults. Although the introduction of combined neoadjuvant chemotherapy has markedly improved survival, the outcome of OS patients with distant metastasis and/or poor response to chemotherapy is still unsatisfactory. Therefore there is a need to develop new therapeutic agents that suppress OS cell proliferation with higher...

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PMID: 19725836
DOI: 10.1111/j.1349-7006.2009.01310.x

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