Article
The effect of apolipoprotein B xbaI polymorphism on plasma lipid response to dietary fat.
European journal of clinical investigation - 1 Aug 2000
López-Miranda J, Marín C, Castro P, Gómez P, González-Amieva A, Paz E, Bravo D, Ordovas J M, Jimenez-Pereperez J, Pérez-Jiménez F
Abstract excerpt
BACKGROUND AND AIMS: Lipid response to dietary fat and cholesterol is, to a large extent, genetically controlled. Apolipoprotein B (apo B) plays a dominant role in cholesterol homeostasis. Several polymorphic sites within or adjacent to the gene locus for apo B have been detected. The X+ allele of the XbaI restriction fragment polymorphism of the apo B gene has been found to be associated with higher serum...
Topics
- Adult
- Alleles
- Apolipoprotein A-I
- Apolipoproteins B
- Body Mass Index
- Cholesterol
- Deoxyribonucleases, Type II Site-Specific
- Diet Records
- Dietary Fats
- Fatty Acids
- Genotype
- Humans
- Lipids
- Male